⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10142104 | 1.00 | — | — | |
| SCHEMBL17722654 | 0.91 | TMPRSS2 (0.34) | — | |
| SCHEMBL10142084 | 0.91 | TMPRSS2 (0.34) | — | |
| SCHEMBL10142421 | 0.86 | — | — | |
| SCHEMBL10142123 | 0.86 | — | — | |
| SCHEMBL10143786 | 0.86 | — | — | |
| SCHEMBL25822051 | 0.84 | — | — | |
| SCHEMBL807680 | 0.84 | TMPRSS2 (0.34) | — | |
| SCHEMBL16479532 | 0.84 | TMPRSS2 (0.34) | — | |
| SCHEMBL12454580 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122356-A1 | METHODS FOR THE PREPARATION OF RIBOSIDES | GILEAD SCIENCES, INC. | 2016-05-05 | — | — | US | disclosed |