Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16321631 | 0.83 | NOTUM (0.33) | CYP17A1NOTUM | |
| SCHEMBL17728508 | 0.76 | — | — | |
| SCHEMBL17728629 | 0.73 | NOTUM (0.35) | CYP17A1NOTUM | |
| SCHEMBL16324422 | 0.73 | CYP17A1 (0.32) | CYP17A1 | |
| SCHEMBL16323932 | 0.72 | CYP17A1 (0.36) | CYP17A1 | |
| SCHEMBL16323410 | 0.69 | CYP17A1 (0.40) | CYP17A1NOTUM | |
| SCHEMBL17728540 | 0.67 | NOTUM (0.35) | NOTUM | |
| SCHEMBL27793766 | 0.64 | — | — | |
| SCHEMBL17728498 | 0.61 | NOTUM (0.30) | NOTUM | |
| SCHEMBL17728484 | 0.59 | NOTUM (0.37) | CYP17A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890139-B2 | CYP17 inhibitors/antiandrogens | ORION CORPORATION (FI) | 2018-02-13 | — | — | US | disclosed |
| US-20160130254-A1 | NOVEL CYP17 INHIBITORS/ANTIANDROGENS | ORION CORPORATION (FI) | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130254-A1 | NOVEL CYP17 INHIBITORS/ANTIANDROGENS | CYP17A1, CYP19A1, CYP21A2 | CYP17A1 1/4885NOTUM 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.