Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.70 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86531 | 0.93 | S1PR1 (0.71) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL86475 | 0.92 | S1PR1 (0.73) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL79712 | 0.92 | S1PR1 (0.69) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL79172 | 0.91 | S1PR1 (0.72) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL86843 | 0.91 | S1PR1 (0.78) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL80972 | 0.89 | S1PR1 (0.76) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL78845 | 0.87 | S1PR1 (0.72) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL80408 | 0.86 | S1PR1 (0.68) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL80215 | 0.86 | S1PR1 (0.71) | S1PR1S1PR3TNNC1S1PR4S1PR5 | |
| SCHEMBL79227 | 0.85 | S1PR1 (0.70) | S1PR1S1PR3TNNC1S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168944-B1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-05-11 | — | — | EP | disclosed |