SCHEMBL17733332

SCHEMBL17733332

CC1(C)OCC(N)(CCc2ccc(OCCCC3CCCc4ccccc43)c(C(F)(F)F)c2)CO1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.36
SIGMAR1 Q99720 2/20 0.35
HPGD P15428 1/20 0.33
TRPV1 Q8NER1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81518 0.83 TRPV1 (0.34) S1PR1SIGMAR1TRPV1
SCHEMBL13463905 0.80 S1PR1 (0.43) S1PR1HPGD
SCHEMBL86401 0.80 S1PR1 (0.56) S1PR1SIGMAR1HPGDTRPV1
Hydrochloric Acid SCHEMBL81050 0.79 S1PR1 (0.55) S1PR1SIGMAR1HPGDTRPV1
SCHEMBL13463908 0.79 S1PR1 (0.42) S1PR1
SCHEMBL13463943 0.78 S1PR1 (0.41) S1PR1SIGMAR1
SCHEMBL13665120 0.77 S1PR1 (0.48) S1PR1HPGD
SCHEMBL13665130 0.77 S1PR1 (0.48) S1PR1HPGD
SCHEMBL12336973 0.77 S1PR1 (0.59) S1PR1HPGD
SCHEMBL12337246 0.77 S1PR1 (0.59) S1PR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2168944-B1 AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2016-05-11 EP disclosed