Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL14248079 | 0.93 | — | — | |
| Dimethyl Sulfoxide SCHEMBL16720928 | 0.93 | — | — | |
| Dimethyl Sulfoxide SCHEMBL59 | 0.93 | — | — | |
| Dimethyl Sulfoxide SCHEMBL17141374 | 0.93 | — | — | |
| Dimethyl Sulfoxide SCHEMBL2856303 | 0.93 | — | — | |
| Dimethyl Sulfoxide SCHEMBL3409 | 0.93 | — | — | |
| Dimethyl Sulfoxide SCHEMBL23457363 | 0.86 | — | — | |
| Dimethyl Sulfoxide SCHEMBL8906090 | 0.86 | — | — | |
| Dimethyl Sulfoxide SCHEMBL10337084 | 0.86 | — | — | |
| Dimethyl Sulfoxide SCHEMBL11665563 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429619-B | Surface-modified porous polyether-ether-ketone artificial skeleton and preparation method thereof | 广西民族大学 | 2023-02-28 | — | — | CN | claimed |
| CN-113429619-A | Surface-modified porous polyether-ether-ketone artificial skeleton and preparation method thereof | 广西民族大学 | 2021-09-24 | — | — | CN | claimed |
| US-10703836-B2 | Synthesis of functionalized polyisobutylenes | Henkel IP & Holding GmbH (DE) | 2020-07-07 | — | — | US | claimed |
| US-20180148523-A1 | Synthesis of Functionalized Polyisobutylenes | HENKEL AG & CO. KGAA (DE) | 2018-05-31 | — | — | US | claimed |
| WO-2008035381-A2 | PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES AS CALCIMIMETICS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| US-4394329-A | PLASTICIZING, EXPLOSIVES, VASODILATION, 2-HYDROXYMETHYL-1,3-PROPANEDIOL NITRATION | THIOKOL CORPORATION (US) | 1983-07-19 | — | — | US | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |
| CN-115813923-A | Compounds for the treatment of neurogenic orthostatic hypotension | 施万生物制药研发IP有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115770244-A | Compounds for the treatment of neurogenic orthostatic hypotension | 施万生物制药研发IP有限责任公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-113429619-B | Surface-modified porous polyether-ether-ketone artificial skeleton and preparation method thereof | 广西民族大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-114502562-A | Novel substituted 6, 7-dihydro-5H-benzo [7] annulene compounds, process for their preparation and their therapeutic use | 赛诺菲 | 2022-05-13 | — | — | CN | disclosed |
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-113429619-A | Surface-modified porous polyether-ether-ketone artificial skeleton and preparation method thereof | 广西民族大学 | 2021-09-24 | — | — | CN | disclosed |
| WO-1997016183-A1 | THIAMORPHINANS WITH NEUROPROTECTIVE ACTIVITY | BIOCHEM PHARMA INC. (CA) | 1997-05-09 | — | — | WO | disclosed |
| CN-1104831-A | Ornithine decarboxylase inhibiting branched aminooxy amino alkane derivatives | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | CN | disclosed |
| EP-0659180-A1 | ANTI-VIRAL SULFUR-ANALOGUES OF 1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL (DEOXYNOJIRIMYCIN) | G.D. SEARLE & CO. (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5342951-A | Inhibiting glycosidase enzymes, antiviral compounds | G.D. SEARLE & CO. (US) | 1994-08-30 | — | — | US | disclosed |
| US-5331096-A | Viricides, HIV, enzyme inhibitors | G. D. SEARLE & CO. (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1994005635-A1 | ANTI-VIRAL SULFUR-ANALOGUES OF 1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL (DEOXYNOJIRIMYCIN) | G.D. SEARLE & CO. (US) | 1994-03-17 | — | — | WO | disclosed |
| US-5268482-A | Containing piperidine ring substituted with ether or sulfide groups | G. D. SEARLE & CO. (US) | 1993-12-07 | — | — | US | disclosed |