SCHEMBL17733552

SCHEMBL17733552

CN1CCN(C2C=CC=CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27702026 0.78
SCHEMBL15161657 0.75
SCHEMBL3583581 0.72 KDM4E (0.34) KDM4ETDP1
SCHEMBL14848237 0.71 KDM4E (0.30) KDM4ETDP1
SCHEMBL13342856 0.68 KDM4E (0.31) KDM4ETDP1
SCHEMBL15088774 0.68 KDM4E (0.34) KDM4ETDP1
SCHEMBL12973999 0.68
SCHEMBL18944363 0.67 KDM4E (0.33) KDM4ETDP1
SCHEMBL10076158 0.67 MC4R (0.38)
SCHEMBL13284314 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1696912-B1 PYRAZOLOPYRIDINES AND ANALOGS THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2016-05-11 EP disclosed