Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58625 | 1.00 | TUBB1 (0.46) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL13681991 | 1.00 | TUBB1 (0.46) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL88749 | 1.00 | TUBB1 (0.46) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL28381670 | 0.95 | TUBB1 (0.47) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL22069909 | 0.95 | TUBB1 (0.47) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL28380575 | 0.95 | TUBB1 (0.47) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL22283984 | 0.95 | TUBB1 (0.47) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL22283983 | 0.95 | TUBB1 (0.47) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL28380576 | 0.95 | TUBB1 (0.47) | TUBB1FKBP1AELANEMEN1KMT2A | |
| SCHEMBL57624 | 0.92 | KMT2A (0.43) | TUBB1FKBP1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374454-B1 | HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER | EISAI R&D MAN CO LTD (JP) | 2016-05-11 | — | — | EP | disclosed |