Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179062 | 0.94 | PDK2 (0.39) | PDK2ESR1ESR2MLNRNR1I2 | |
| SCHEMBL14729215 | 0.93 | PDK2 (0.40) | PDK2ESR1ESR2MLNRNR1I2 | |
| SCHEMBL10092991 | 0.92 | PDK2 (0.36) | PDK2ESR1ESR2MLNRNR1I2 | |
| SCHEMBL14340088 | 0.91 | PDK2 (0.41) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL29462237 | 0.91 | PDK2 (0.41) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL1336508 | 0.91 | PDK2 (0.41) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL17970833 | 0.91 | PDK2 (0.41) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL17447205 | 0.90 | PDK2 (0.40) | PDK2ESR1ESR2MLNRNR1I2 | |
| SCHEMBL19531987 | 0.90 | PDK2 (0.39) | PDK2ESR1ESR2MLNRNR1I2 | |
| SCHEMBL19531981 | 0.89 | ESR2 (0.39) | PDK2ESR2MLNRNR1I2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160131985-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20160131985-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-05-12 | — | — | US | disclosed |