SCHEMBL1774204

SCHEMBL1774204

O=C1CC(O)NC(=O)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332160 0.81
SCHEMBL24763724 0.73
SCHEMBL19226330 0.72
SCHEMBL19221481 0.72
SCHEMBL124233 0.71 CRBN (0.36)
SCHEMBL1061579 0.71 CRBN (0.36)
SCHEMBL13033027 0.70
SCHEMBL21731425 0.70
SCHEMBL5433985 0.70
SCHEMBL8285795 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3896067-A1 NOVEL POLYCYCLIC COMPOUND Eutec New Materials Technology (Suzhou) Co., Ltd (CN) 2021-10-20 EP disclosed
US-20170355712-A1 AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS Epizyme, Inc. 2017-12-14 US disclosed
EP-2457955-B1 Trisazo dyes for paper dyeing KEMIRA OYJ (FI) 2017-08-09 EP disclosed
US-20170056528-A1 MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF MODERNATX, INC. 2017-03-02 US disclosed
CN-102712619-B 5-hydroxy pyrimidine-4-carboxamides derivatives DAIICHI SANKYO Co.,Ltd. (JP) 2015-11-25 CN disclosed
EP-2492266-B1 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2015-08-26 EP disclosed
US-8785462-B2 5-hydroxypyrimidine-4-carboxamide derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-07-22 US disclosed
US-20120220609-A1 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2012-08-30 US disclosed
EP-2492266-A1 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2012-08-29 EP disclosed
US-20110112103-A1 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-05-12 US disclosed
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed
US-3925386-A 6-Hydroxy-dihydro-uracils, process for their preparation BAYER AG 1975-12-09 US disclosed
US-3925386-A 6-Hydroxy-dihydro-uracils, process for their preparation BAYER AG 1975-12-09 US disclosed