Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 18/20 | 1.00 |
| ▸ | RARG | P13631 | 18/20 | 1.00 |
| ▸ | RARA | P10276 | 14/20 | 1.00 |
| ▸ | RXRA | P19793 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | CYP26A1 | O43174 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | MTOR | P42345 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836848 | 1.00 | RARB (1.00) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL345071 | 1.00 | RARB (1.00) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL2307487 | 1.00 | RARB (1.00) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL9419009 | 0.95 | RARB (0.90) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL9418968 | 0.95 | RARB (0.90) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL5304297 | 0.92 | RARB (0.85) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL5304306 | 0.92 | RARB (0.85) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL12498687 | 0.92 | RARB (1.00) | RARBRARGRARARXRAKDM4E | |
| SCHEMBL5304300 | 0.92 | RARB (0.85) | RARBRARGRARARXRAKDM4E | |
| Tromethamine SCHEMBL27599878 | 0.91 | RARB (0.82) | RARBRARGRARARXRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4155 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3841097-B1 | 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER | BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) | 2026-05-20 | — | — | EP | claimed |
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | TRAILHEAD BIOSYSTEMS INC (US) | 2026-05-07 | — | — | US | claimed |
| EP-4735120-A2 | CHEMICALLY INDUCED REPROGRAMMING TO REVERSE AGING | President and Fellows of Harvard College (US) | 2026-05-06 | — | — | EP | claimed |
| EP-4724119-A2 | LIVER SUPPORT SYSTEMS AND METHODS OF USE | Kanto Biomedicines, Inc. (US) | 2026-04-15 | — | — | EP | claimed |
| US-12589189-B2 | Use of retinoic acid receptor (RAR) agonists for reversing, preventing, or delaying calcification of aortic valve | INSERM (INSTITUTE NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE) (FR) | 2026-03-31 | — | — | US | claimed |
| EP-4713433-A2 | LIVER ORGANOIDS WITH INTRAHEPATIC SYMPATHETIC NERVES, AND METHODS OF USE THEREOF | Children's Hospital Medical Center (US) | 2026-03-25 | — | — | EP | claimed |
| EP-4037672-B1 | RETINOIC ACID RECEPTOR (RAR) AGONISTS FOR REVERSING, PREVENTING, OR DELAYING CALCIFICATION OF AORTIC VALVE | INST NAT SANTE RECH MED (FR) | 2026-03-11 | — | — | EP | claimed |
| US-12565640-B2 | Method for inducing ureteric bud-like tissue | KYOTO UNIVERSITY (JP) | 2026-03-03 | — | — | US | claimed |
| EP-4689067-A2 | CLINICAL-GRADE ORGANOIDS | Children's Hospital Medical Center (US) | 2026-02-11 | — | — | EP | claimed |
| EP-3784232-B1 | IMPROVED METHODS FOR INDUCING TISSUE REGENERATION AND SENOLYSIS IN MAMMALIAN CELLS | AGEX THERAPEUTICS INC (US) | 2026-02-11 | — | — | EP | claimed |
| EP-0263492-B1 | RETINOIDS, THEIR PREPARATION AND USE AS PHARMACEUTICAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | claimed |
| US-4900478-A | SKIN DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | claimed |
| US-4888342-A | APPLYING RETINOID | KLIGMAN ALBERT M (US) | 1989-12-19 | — | — | US | claimed |
| US-4877805-A | REVERSING COLLAGEN FIBER LOSS BY APPLYING TO FACE | KLIGMAN ALBERT M (US) | 1989-10-31 | — | — | US | claimed |
| EP-0263492-A1 | Retinoids, their preparation and use as pharmaceutical compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1988-04-13 | — | — | EP | claimed |
| WO-1988000466-A1 | METHODS FOR TREATMENT OF SUNDAMAGED HUMAN SKIN WITH RETINOIDS | KLIGMAN ALBERT M (US) | 1988-01-28 | — | — | WO | claimed |
| EP-0253393-A2 | Methods for treatment of sundamaged human skin with retinoids | Kligman, Albert M. (US) | 1988-01-20 | — | — | EP | claimed |
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | claimed |
| EP-0002742-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THESE STILBENE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-04-14 | — | — | EP | claimed |
| EP-0002742-A1 | Stilbene derivatives, their preparation and medicines containing these stilbene derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | claimed |