SCHEMBL17744873

SCHEMBL17744873

Nc1ccc(OC(=O)c2ccc(C(=O)Oc3ccc(N)cc3-c3ccccc3N)cc2)c(-c2ccccc2N)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.43
▸ TSHR P16473 2/20 0.43
▸ KMT2A Q03164 4/20 0.42
▸ PTGDR2 Q9Y5Y4 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MAPT P10636 2/20 0.39
▸ SLC6A3 Q01959 1/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ MAPK1 P28482 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ TOP1 P11387 1/20 0.38
▸ SERPINE1 P05121 1/20 0.38
▸ PTPRC P08575 2/20 0.38
▸ PRSS1 P07477 2/20 0.38
▸ ACR P10323 2/20 0.38
▸ GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744874 0.94 KMT2A (0.41) SMN1; SMN2TSHRKMT2APTGDR2MAPT
SCHEMBL17744781 0.91 KMT2A (0.43) SMN1; SMN2TSHRKMT2APTGDR2ALDH1A1
SCHEMBL17744806 0.88 SMN1; SMN2 (0.43) SMN1; SMN2TSHRKMT2APTGDR2ALDH1A1
SCHEMBL17744782 0.86 KDM4C (0.43) SMN1; SMN2TSHRKMT2APTGDR2MAPT
SCHEMBL3785811 0.83 PTGDR2 (0.42) SMN1; SMN2TSHRKMT2APTGDR2ALDH1A1
SCHEMBL17744808 0.83 KDM4E (0.44) SMN1; SMN2KMT2APTGDR2ALDH1A1MAPT
SCHEMBL21583269 0.82 PTGDR2 (0.58) SMN1; SMN2KMT2APTGDR2MAPTSLC6A3
SCHEMBL29441965 0.82 PTGDR2 (0.58) SMN1; SMN2KMT2APTGDR2MAPTSLC6A3
SCHEMBL30335393 0.81 KMT2A (0.56) SMN1; SMN2TSHRKMT2AALDH1A1L3MBTL1
SCHEMBL27639137 0.78 KMT2A (0.51) SMN1; SMN2TSHRKMT2APTGDR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 — — US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 — — CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 — — EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 — — US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 — — EP disclosed
CN-105392838-A Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES 2016-03-09 — — CN disclosed
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