Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19306615 | 0.89 | MAPT (0.47) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31686443 | 0.82 | ADORA2A (0.44) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| Pyrazole SCHEMBL28225731 | 0.82 | MAPT (0.43) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6684736 | 0.80 | ADORA2A (0.42) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14295796 | 0.80 | HTT (0.50) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2549734 | 0.78 | ADORA2A (0.41) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9354812 | 0.78 | ADORA2A (0.41) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20640620 | 0.78 | MAPT (0.51) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9354794 | 0.78 | HTT (0.49) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13866122 | 0.78 | HTT (0.49) | HTTCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777322-B | Biodegradable closed isocyanate chain extender, and preparation method and application thereof | 浙江工业大学 | 2025-03-04 | — | — | CN | claimed |
| CN-117777322-A | Biodegradable closed isocyanate chain extender, and preparation method and application thereof | 浙江工业大学 | 2024-03-29 | — | — | CN | claimed |
| CN-112876689-B | Metal-organic framework material and preparation method and application thereof | 江苏科技大学 | 2022-05-10 | — | — | CN | claimed |
| WO-2022039927-A1 | ONE-COMPONENT WATERBORNE POLYURETHANE SELF-HEALING COATINGS USING HYDROPHOBIC BLOCKED POLYISOCYANATES | COVESTRO LLC (US) | 2022-02-24 | — | — | WO | claimed |
| CN-112876689-A | Metal-organic framework material and preparation method and application thereof | 江苏科技大学 | 2021-06-01 | — | — | CN | claimed |
| EP-1535939-B1 | Blocked polyisocyanate | BAYER MATERIALSCIENCE LLC (US) | 2008-05-21 | — | — | EP | claimed |
| US-20070149750-A1 | Solid powder coating crosslinker | BAYER MATERIALSCIENCE LLC | 2007-06-28 | — | — | US | claimed |
| US-20050245718-A1 | Solid powder coating crosslinker | BAYER MATERIALSCIENCE LLC | 2005-11-03 | — | — | US | claimed |
| EP-1535939-A1 | Blocked polyisocyanate | Bayer MaterialScience LLC (US) | 2005-06-01 | — | — | EP | claimed |
| US-20050113548-A1 | Solid powder coating crosslinker | BAYER MATERIALSCIENCE LLC | 2005-05-26 | — | — | US | claimed |
| US-6448363-B1 | TRIAZOLE AND PYRAZOLE BLOCKED; FOR PRODUCTION OF POLYURETHANE POWDER COATINGS | DEGUSSA AG (DE) | 2002-09-10 | — | — | US | claimed |
| US-20020055603-A1 | Coating composition | FIGGE HANS-JURGEN (DE) | 2002-05-09 | — | — | US | claimed |
| US-6355761-B1 | Coating composition | BASF COATINGS AG (DE) | 2002-03-12 | — | — | US | claimed |
| US-20020028948-A1 | Process for preparing highly reactive (semi) crystalline and amorphous blocked polyisocyanates | DEGUSSA AG (DE) | 2002-03-07 | — | — | US | claimed |
| EP-1170316-A1 | Process for producing highly reactive (semi)crystalline and amorphous blocked polyisocyanates | Degussa AG (DE) | 2002-01-09 | — | — | EP | claimed |
| EP-0749448-B1 | USE OF PYRAZOLE-BLOCKED POLYISOCYANATES IN ONE-COMPONENT CLEAR COATINGS | ARCO CHEM TECH (US) | 2001-05-30 | — | — | EP | claimed |
| EP-0959085-A1 | Coatings containing blocked polyurethane prepolymers and their use | BASF Coatings AG (DE) | 1999-11-24 | — | — | EP | claimed |
| EP-0749448-A1 | ISOCYANATE-CROSSLINKED COATINGS HAVING REDUCED YELLOWING | OLIN CORPORATION (US) | 1996-12-27 | — | — | EP | claimed |
| EP-0749448-A4 | ISOCYANATE-CROSSLINKED COATINGS HAVING REDUCED YELLOWING | OLIN CORP (US) | 1996-06-19 | — | — | EP | claimed |
| WO-1995006674-A1 | ISOCYANATE-CROSSLINKED COATINGS HAVING REDUCED YELLOWING | OLIN CORPORATION (US) | 1995-03-09 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028948-A1 | Process for preparing highly reactive (semi) crystalline and amorphous blocked polyisocyanates | RIN1, C1R, C1S | HTT 2039/4885CYP1A2 149/4885CYP2D6 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.