Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17745928 | 0.89 | GALR2 (0.41) | GBA1MAPTSMN1; SMN2GALR2LMNA | |
| SCHEMBL12486170 | 0.88 | MAPK1 (0.45) | MAPK1GBA1KCNH3PAK4PAK1 | |
| SCHEMBL12484910 | 0.87 | GBA1 (0.46) | MAPK1GBA1KCNH3PAK4PAK1 | |
| SCHEMBL12484076 | 0.87 | MAPK1 (0.44) | MAPK1GBA1KCNH3CTSLCTSB | |
| SCHEMBL12484082 | 0.87 | MAPK1 (0.44) | MAPK1GBA1KCNH3CTSLCTSB | |
| SCHEMBL12484904 | 0.87 | GBA1 (0.46) | MAPK1GBA1KCNH3PAK4PAK1 | |
| SCHEMBL12486751 | 0.86 | MAPK1 (0.45) | MAPK1GBA1KCNH3PAK4PAK1 | |
| SCHEMBL12485319 | 0.83 | GBA1 (0.48) | MAPK1GBA1KCNH3PAK4PAK1 | |
| SCHEMBL12486104 | 0.82 | GALR2 (0.56) | MAPK1GBA1KCNH3MTORSMG1 | |
| SCHEMBL12485520 | 0.81 | MTOR (0.59) | MAPK1GBA1VSIRMTORSMG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678332-B1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2016-05-18 | — | — | EP | disclosed |