Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19990741 | 1.00 | GLP1R (0.44) | GLP1REPHX2FOLH1TTR | |
| SCHEMBL17747012 | 1.00 | GLP1R (0.44) | GLP1REPHX2FOLH1TTR | |
| SCHEMBL19990825 | 1.00 | GLP1R (0.44) | GLP1REPHX2FOLH1TTR | |
| SCHEMBL17747047 | 0.90 | GLP1R (0.55) | GLP1RFOLH1 | |
| SCHEMBL17747022 | 0.90 | GLP1R (0.55) | GLP1RFOLH1 | |
| SCHEMBL17747024 | 0.90 | GLP1R (0.55) | GLP1RFOLH1 | |
| SCHEMBL19990821 | 0.90 | GLP1R (0.55) | GLP1RFOLH1 | |
| SCHEMBL17747058 | 0.90 | GLP1R (0.55) | GLP1RFOLH1 | |
| SCHEMBL21866606 | 0.90 | GLP1R (0.55) | GLP1RFOLH1 | |
| SCHEMBL19990740 | 0.90 | GLP1R (0.55) | GLP1RFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952434-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-09 | — | — | US | disclosed |
| US-20230101323-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-03-30 | — | — | US | disclosed |
| US-11358988-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-06-14 | — | — | US | disclosed |
| EP-3778622-A1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3218392-B1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2020-07-29 | — | — | EP | disclosed |
| US-20200216498-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-07-09 | — | — | US | disclosed |
| US-10633419-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180086793-A1 | IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-29 | — | — | US | disclosed |
| US-9856292-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-02 | — | — | US | disclosed |
| EP-3218392-A1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20160137696-A1 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY | 2016-05-19 | — | — | US | disclosed |
| WO-2016077518-A1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952434-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | GLP1R 4424/4885EPHX2 2816/4885FOLH1 550/4885 |
| US-20160137696-A1 | Immunomodulators | CD74, ICOS, HAVCR2 | GLP1R 4424/4885EPHX2 2816/4885FOLH1 550/4885 |
| US-20230101323-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | GLP1R 4424/4885EPHX2 2816/4885FOLH1 550/4885 |
| US-10633419-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | GLP1R 4424/4885EPHX2 2816/4885FOLH1 550/4885 |
| US-11358988-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | GLP1R 4424/4885EPHX2 2816/4885FOLH1 550/4885 |
| US-20180086793-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | GLP1R 4424/4885EPHX2 2816/4885FOLH1 550/4885 |
| US-20200216498-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | GLP1R 4424/4885EPHX2 2816/4885FOLH1 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.