Butyric Acid

Butyric Acid

SCHEMBL17748852

C=CC(O)CCC=CC.CCCC(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
BLM P54132 3/20 0.39
SLC6A2 P23975 2/20 0.39
CYP2C19 P33261 2/20 0.39
KMT2A Q03164 2/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 1/20 0.39
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
PPARG P37231 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869791 0.83
SCHEMBL869790 0.83
SCHEMBL31275238 0.83
SCHEMBL17748834 0.79 SLC6A2 (0.32) NFKB1BLMSLC6A2CYP2C19KMT2A
SCHEMBL17748832 0.79 SLC6A2 (0.32) NFKB1BLMSLC6A2CYP2C19KMT2A
SCHEMBL1834214 0.79 PPARG (0.30) PPARGPPARDPPARA
SCHEMBL31719711 0.79 PPARG (0.30) PPARGPPARDPPARA
SCHEMBL15796546 0.79 PPARG (0.30) PPARGPPARDPPARA
Butyric Acid SCHEMBL28654816 0.77 FFAR3 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL27702877 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455284-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2019-03-20 EP disclosed
WO-2017196763-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2017-11-16 WO disclosed
WO-2017196762-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2017-11-16 WO disclosed
EP-3218425-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2017-09-20 EP disclosed
WO-2016077513-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2016-05-19 WO disclosed