Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | F8 | P00451 | 1/20 | 0.70 |
| ▸ | F5 | P12259 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | XBP1 | P17861 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17761945 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17749575 | 0.91 | TSHR (0.60) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17749638 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17749621 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17761753 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17749495 | 0.84 | MAPT (0.55) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17761818 | 0.84 | TP53 (0.67) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17749511 | 0.84 | TP53 (0.67) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17749541 | 0.83 | MAPT (0.56) | SMN1; SMN2MAPTTP53F8F5 | |
| SCHEMBL17749641 | 0.83 | MAPT (0.56) | SMN1; SMN2MAPTTP53F8F5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016077541-A1 | NOVEL ANTI-INFECTIVE COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016077541-A1 | NOVEL ANTI-INFECTIVE COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-05-19 | — | — | WO | disclosed |