Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.67 |
| ▸ | PPIB | P23284 | 1/20 | 0.67 |
| ▸ | PPIA | P62937 | 1/20 | 0.67 |
| ▸ | PPIG | Q13427 | 1/20 | 0.67 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | IRS1 | P35568 | 1/20 | 0.44 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177112 | 0.83 | S1PR1 (0.58) | SPHK1S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL14617663 | 0.83 | PPID (0.78) | PPIDPPIBPPIAPPIG | |
| SCHEMBL2034522 | 0.82 | PPID (0.76) | PPIDPPIBPPIAPPIG | |
| SCHEMBL2036646 | 0.81 | PPID (0.74) | PPIDPPIBPPIAPPIGS1PR1 | |
| SCHEMBL12643634 | 0.81 | PPID (0.74) | PPIDPPIBPPIAPPIG | |
| SCHEMBL2041585 | 0.81 | PPID (0.74) | PPIDPPIBPPIAPPIG | |
| SCHEMBL2042945 | 0.81 | PPID (0.74) | PPIDPPIBPPIAPPIGPPARG | |
| SCHEMBL2044119 | 0.81 | PPID (1.00) | PPIDPPIBPPIAPPIG | |
| SCHEMBL12643825 | 0.80 | PPID (1.00) | PPIDPPIBPPIAPPIG | |
| SCHEMBL2041326 | 0.80 | PPID (0.72) | PPIDPPIBPPIAPPIG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-9193716-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2015-11-24 | — | — | US | disclosed |
| US-20140066427-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD. (AU) | 2014-03-06 | — | — | US | disclosed |
| US-8592399-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2013-11-26 | — | — | US | disclosed |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD (AU) | 2011-12-29 | — | — | US | disclosed |
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | PPID 3448/4885PPIB 3673/4885PPIA 3562/4885 |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | S1PR1, S1PR5, S1PR2 | PPID 3448/4885PPIB 3673/4885PPIA 3562/4885 |
| US-20140066427-A1 | S1P Receptors Modulators and Their Use Thereof | S1PR1, S1PR2, S1PR5 | PPID 4225/4885PPIB 4323/4885PPIA 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.