Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14013420 | 0.90 | MEN1 (0.41) | MEN1BLMKMT2ATHRBRECQL | |
| Hydrochloric Acid SCHEMBL4121346 | 0.89 | MEN1 (0.41) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14013421 | 0.88 | MEN1 (0.49) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14013422 | 0.87 | MEN1 (0.46) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL4107893 | 0.87 | P2RY6 (0.47) | MEN1BLMKMT2ATHRBRECQL | |
| Hydrochloric Acid SCHEMBL4109334 | 0.86 | MEN1 (0.45) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14013310 | 0.85 | MEN1 (0.41) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14013311 | 0.82 | MEN1 (0.49) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL19927822 | 0.82 | P2RY6 (0.48) | MEN1BLMKMT2ATHRBRECQL | |
| SCHEMBL14013314 | 0.81 | MEN1 (0.45) | MEN1BLMKMT2ATHRBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |