Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAF1 | P21675 | 20/20 | 0.65 |
| ▸ | CECR2 | Q9BXF3 | 20/20 | 0.65 |
| ▸ | BRD9 | Q9H8M2 | 18/20 | 0.65 |
| ▸ | BRD4 | O60885 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17753732 | 0.80 | TAF1 (0.70) | TAF1CECR2BRD9BRD4 | |
| Hydrochloric Acid SCHEMBL17749028 | 0.79 | TAF1 (0.69) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL19652268 | 0.79 | TAF1 (1.00) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL17753706 | 0.77 | TAF1 (0.84) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL17753819 | 0.77 | TAF1 (0.94) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL17753856 | 0.77 | TAF1 (1.00) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL17753687 | 0.76 | TAF1 (0.74) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL17753862 | 0.76 | TAF1 (0.76) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL17753831 | 0.74 | TAF1 (0.80) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL17754017 | 0.74 | TAF1 (1.00) | TAF1CECR2BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016077375-A1 | BROMODOMAIN INHIBITORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-05-19 | — | — | WO | disclosed |