Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754755 | 0.88 | PRKDC (0.33) | — | |
| SCHEMBL17759141 | 0.88 | RET (0.30) | — | |
| SCHEMBL17754756 | 0.87 | PRKDC (0.31) | PDK2 | |
| SCHEMBL17754748 | 0.87 | NPC1 (0.30) | NPC1 | |
| SCHEMBL17754750 | 0.84 | AAK1 (0.31) | — | |
| SCHEMBL17754751 | 0.82 | AAK1 (0.30) | — | |
| SCHEMBL17754749 | 0.82 | — | — | |
| SCHEMBL17759148 | 0.79 | — | — | |
| SCHEMBL17759301 | 0.78 | PDK2 (0.32) | PDK2KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL17758926 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210083206-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2021-03-18 | — | — | US | disclosed |
| US-10868261-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-12-15 | — | — | US | disclosed |
| US-20160141522-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-20160141522-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10868261-B2 | Organic electroluminescent materials and devices | ICOSLG, CD274, PDCD1 | JAK2 2083/4885JAK1 2500/4885TYK2 1139/4885 |
| US-20160141522-A1 | Organic Electroluminescent Materials and Devices | EED, ICOSLG, OCIAD1 | JAK2 1846/4885JAK1 2866/4885TYK2 1812/4885 |
| US-20210083206-A1 | Organic Electroluminescent Materials and Devices | EED, ICOSLG, OCIAD1 | JAK2 1846/4885JAK1 2866/4885TYK2 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.