SCHEMBL17755608

SCHEMBL17755608

c1ccc(-c2cc(-c3cnccn3)nc(-c3cnccn3)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.62
▸ PIM1 P11309 2/20 0.51
▸ METAP2 P50579 1/20 0.46
▸ CYP3A4 P08684 2/20 0.45
▸ PIM2 Q9P1W9 2/20 0.43
▸ CYP2A6 P11509 1/20 0.43
▸ MAPK10 P53779 1/20 0.41
▸ GABRA1 P14867 1/20 0.40
▸ GABRG2 P18507 1/20 0.40
▸ GABRB3 P28472 1/20 0.40
▸ GABRA5 P31644 1/20 0.40
▸ GABRA3 P34903 1/20 0.40
▸ NOTUM Q6P988 1/20 0.40
▸ KDR P35968 1/20 0.40
▸ CCR1 P32246 1/20 0.39
▸ CCR5 P51681 1/20 0.39
▸ CCR8 P51685 1/20 0.39
▸ ASIC3 Q9UHC3 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29482241 1.00 CYP19A1 (0.62) CYP19A1PIM1METAP2CYP3A4PIM2
SCHEMBL18334166 0.92 CYP19A1 (0.54) CYP19A1PIM1METAP2CYP3A4PIM2
SCHEMBL17755609 0.89 CYP19A1 (0.51) CYP19A1PIM1METAP2CYP3A4PIM2
SCHEMBL30023117 0.87 CYP19A1 (0.46) CYP19A1PIM1CYP3A4PIM2NOTUM
SCHEMBL32677335 0.84 CYP2A6 (0.55) CYP19A1PIM1METAP2CYP3A4PIM2
SCHEMBL24589775 0.83 MEN1 (0.53) CYP19A1PIM1METAP2CYP3A4LMNA
SCHEMBL17746913 0.82 CYP19A1 (0.42) CYP19A1PIM1PIM2MEN1RAB9A
SCHEMBL29661988 0.82 NPC1 (0.55) CYP19A1PIM1CYP3A4PIM2CCR1
SCHEMBL18334161 0.82 CYP19A1 (0.44) CYP19A1PIM1METAP2CYP3A4MAPK10
SCHEMBL18334156 0.81 CYP19A1 (0.43) CYP19A1PIM1METAP2CYP3A4PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3024050-B1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO LTD (KR) 2020-08-12 — — EP disclosed
US-9978945-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2018-05-22 — — US disclosed
US-9978945-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2018-05-22 — — US disclosed
US-20160141502-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-05-19 — — US disclosed
US-20160141502-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2016-05-19 — — US disclosed
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