Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 20/20 | 1.00 |
| ▸ | CECR2 | Q9BXF3 | 6/20 | 0.76 |
| ▸ | BRD4 | O60885 | 5/20 | 0.76 |
| ▸ | TAF1 | P21675 | 5/20 | 0.76 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758528 | 0.88 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL17749890 | 0.86 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL17749891 | 0.86 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL19657253 | 0.85 | BRD9 (0.73) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL17758527 | 0.84 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL17749808 | 0.84 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL30073248 | 0.84 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL17749680 | 0.83 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL17749678 | 0.83 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 | |
| SCHEMBL30073327 | 0.83 | BRD9 (1.00) | BRD9CECR2BRD4TAF1BRD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | claimed |
| EP-3218375-B1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH INC (US) | 2022-04-27 | — | — | EP | claimed |
| US-10183009-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-01-22 | — | — | US | claimed |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | claimed |
| CN-116003409-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-107207493-B | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115583947-A | Substituted pyrrolopyridines as bromodomain inhibitors | 基因泰克公司 | 2023-01-10 | — | — | CN | disclosed |
| EP-3218375-B1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH INC (US) | 2022-04-27 | — | — | EP | disclosed |
| US-10183009-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-10183009-B2 | Therapeutic compounds and uses thereof | GENENTECH, INC. (US) | 2019-01-22 | — | — | US | disclosed |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2017-11-30 | — | — | US | disclosed |
| WO-2016077378-A1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH, INC. (US) | 2016-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10183009-B2 | Therapeutic compounds and uses thereof | BRD4, BRDT, BRPF3 | BRD9 12/4885CECR2 246/4885BRD4 1/4885 |
| US-20170340605-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BRD4, BRDT, BRPF3 | BRD9 12/4885CECR2 246/4885BRD4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.