SCHEMBL1775874

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24319168	0.94	HRH4 (0.65)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL19548104	0.85	SMN1; SMN2 (0.61)	HRH4ALDH1A1TSHR
	SCHEMBL1774531	0.83	CYP2C19 (0.61)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL12497703	0.82	HRH4 (0.57)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL27267881	0.82	HRH4 (0.54)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL4953668	0.81	HRH4 (0.55)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL4953660	0.81	HRH4 (0.55)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL1774811	0.81	CYP1A2 (0.57)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL807737	0.81	HRH4 (0.59)	HRH4HRH3HRH2CYP1A2ALDH1A1
	SCHEMBL27363158	0.79	HRH4 (0.51)	HRH4HRH3HRH2CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.