Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADH5 | P11766 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21695614 | 0.85 | IDO1 (0.50) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL7280094 | 0.82 | CYP3A4 (0.67) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL29488338 | 0.81 | IDO1 (0.61) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL3118463 | 0.81 | IDO1 (0.61) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL939912 | 0.81 | IDO1 (0.61) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL17773158 | 0.79 | IDO1 (0.55) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL10851507 | 0.79 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL5868840 | 0.79 | HTT (0.69) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| SCHEMBL13320411 | 0.79 | IDO1 (0.55) | PDE4APDE4BPDE4CPDE4DIDO1 | |
| Hydrochloric Acid SCHEMBL5869171 | 0.78 | IDO1 (0.62) | PDE4APDE4BPDE4CPDE4DIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218373-B1 | ANTI-HCMV COMPOSITIONS AND METHODS | EVRYS BIO LLC (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2016077232-A2 | ANTI-HCMV COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2016-05-19 | — | — | WO | disclosed |