Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | CCR8 | P51685 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17759096 | 0.90 | CCR1 (0.34) | PDK2NPC1SMN1; SMN2PKMRAB9A | |
| SCHEMBL17759139 | 0.90 | PDK2 (0.33) | PDK2NPC1SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL17759089 | 0.88 | PDK2 (0.35) | PDK2NPC1SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL17759218 | 0.87 | CCR1 (0.33) | CCR1CCR5CCR8 | |
| SCHEMBL17759133 | 0.86 | NPC1 (0.36) | PDK2NPC1SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL17759124 | 0.86 | ESR1 (0.30) | — | |
| SCHEMBL17759185 | 0.86 | PDK2 (0.32) | PDK2 | |
| SCHEMBL17759135 | 0.84 | PDK2 (0.33) | PDK2NPC1SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL17759165 | 0.83 | KCNA3 (0.32) | PDK2NPC1SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL17758973 | 0.82 | ALOX5AP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160141522-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160141522-A1 | Organic Electroluminescent Materials and Devices | EED, ICOSLG, OCIAD1 | PDK2 174/4885NPC1 4554/4885SMN1; SMN2 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.