Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760696 | 0.86 | TSHR (0.55) | TSHRTHRBALDH1A1 | |
| SCHEMBL20144633 | 0.81 | TSHR (0.58) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL17760684 | 0.80 | TSHR (0.57) | TSHRTHRBALDH1A1ZDHHC7POLB | |
| SCHEMBL17760682 | 0.79 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL16573 | 0.79 | — | — | |
| SCHEMBL21772349 | 0.79 | TSHR (0.69) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9502238 | 0.79 | TSHR (0.78) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL31065018 | 0.79 | TSHR (0.78) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5066178 | 0.77 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Hydrogen Sulfide SCHEMBL6879353 | 0.77 | TSHR (0.67) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174159-B2 | Functional polymers | THE UNIVERSITY OF AKRON | 2019-01-08 | — | — | US | disclosed |
| US-20170335059-A1 | FUNCTIONAL POLYMERS | THE UNIVERSITY OF AKRON | 2017-11-23 | — | — | US | disclosed |
| WO-2016070175-A1 | FUNCTIONAL POLYMERS | THE UNIVERSITY OF AKRON (US) | 2016-05-06 | — | — | WO | disclosed |