Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.43 |
| ▸ | CDC25B | P30305 | 8/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.41 |
| ▸ | GJB2 | P29033 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776703 | 1.00 | PTPN1 (0.43) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1775989 | 1.00 | PTPN1 (0.43) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL5568194 | 1.00 | PTPN1 (0.43) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1776276 | 1.00 | PTPN1 (0.43) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1776279 | 1.00 | PTPN1 (0.43) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1776048 | 0.94 | PTPN1 (0.42) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1776050 | 0.94 | PTPN1 (0.42) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1775584 | 0.94 | PTPN1 (0.48) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1775581 | 0.94 | PTPN1 (0.48) | PTPN1PTPN2PTPN11CDC25BPTPN6 | |
| SCHEMBL1778351 | 0.94 | PTPN1 (0.46) | PTPN1PTPN2PTPN11CDC25BPTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943584-B2 | Medicinal composition containing diabetes remedy | SANKYO COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |
| EP-1589023-B1 | OLIGOSACCHARIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |