Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.74 |
| ▸ | CNR1 | P21554 | 5/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226284 | 0.85 | CNR2 (1.00) | CNR2CNR1SCN9A | |
| SCHEMBL17763894 | 0.85 | CNR2 (0.72) | CNR2CNR1SCN9AFPR2 | |
| SCHEMBL17764048 | 0.84 | CNR2 (0.73) | CNR2CNR1 | |
| SCHEMBL17764030 | 0.83 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL17764013 | 0.82 | CNR2 (0.73) | CNR2CNR1 | |
| SCHEMBL17763959 | 0.81 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL17763966 | 0.77 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL17764036 | 0.77 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL17763933 | 0.74 | CNR2 (0.69) | CNR2CNR1SCN9AFPR2 | |
| SCHEMBL17763939 | 0.74 | CNR2 (0.76) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718266-B9 | PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2016-09-28 | — | — | EP | claimed |
| EP-2718266-B1 | PYRIDIN-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2016-05-25 | — | — | EP | claimed |