Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.41 |
| ▸ | ESR1 | P03372 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983886 | 0.84 | KDM1A (0.50) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL11860489 | 0.82 | KMT2A (0.48) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL11865942 | 0.80 | ESR2 (0.52) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL1513874 | 0.78 | MEN1 (0.50) | KDM1AMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL10486574 | 0.77 | ESR2 (0.47) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL16883880 | 0.77 | ESR2 (0.47) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL19343309 | 0.75 | KDM1A (0.42) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL16885987 | 0.75 | KDM1A (0.42) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL16883879 | 0.75 | KDM1A (0.42) | KDM1AESR2ESR1MEN1KMT2A | |
| SCHEMBL9861182 | 0.75 | ESR2 (0.48) | KDM1AESR2ESR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652000-B1 | POLYURETHANE AND POLYISOCYANURATE FOAMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-05-25 | — | — | EP | disclosed |
| CN-1129626-C | Polyols for the preparation of water-blown rigid polyurethane foams | DOW CHEMICAL CO (US) | 2003-12-03 | — | — | CN | disclosed |
| CN-1323327-A | Polyols useful for preparing water blown rigid polyurethane foam | DOW CHEMICAL CO (US) | 2001-11-21 | — | — | CN | disclosed |