Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | CPT2 | P23786 | 2/20 | 0.35 |
| ▸ | CPT1A | P50416 | 2/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778471 | 1.00 | TRPV1 (0.35) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL17769667 | 1.00 | TRPV1 (0.35) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL20550364 | 1.00 | TRPV1 (0.35) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL17769718 | 1.00 | TRPV1 (0.35) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL17769715 | 1.00 | TRPV1 (0.35) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL17778375 | 0.96 | CPT2 (0.36) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL20550521 | 0.96 | CPT2 (0.36) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL17778507 | 0.96 | CPT2 (0.36) | TRPV1CPT2CPT1ACPT1BLMNA | |
| SCHEMBL17778465 | 0.92 | KDM4E (0.34) | CPT2CPT1ACPT1BLMNAMAPT | |
| SCHEMBL20550606 | 0.92 | KDM4E (0.34) | CPT2CPT1ACPT1BLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3220918-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2017-09-27 | — | — | EP | disclosed |
| WO-2016079712-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |