Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.43 |
| ▸ | MME | P08473 | 5/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12527695 | 1.00 | ACE (0.43) | ACEMMEAPPFPR1FPR2 | |
| SCHEMBL17771392 | 0.91 | ACE (0.40) | ACEMMEAPP | |
| SCHEMBL12526761 | 0.91 | ACE (0.40) | ACEMMEAPP | |
| SCHEMBL17771418 | 0.91 | ACE (0.40) | ACEMMEAPP | |
| SCHEMBL17771412 | 0.91 | ACE (0.48) | ACEMMEAPP | |
| SCHEMBL12528474 | 0.91 | ACE (0.48) | ACEMMEAPP | |
| SCHEMBL12528549 | 0.89 | ACE (0.49) | ACEMMEAPP | |
| SCHEMBL17771415 | 0.89 | ACE (0.39) | ACEMMEAPPFPR2 | |
| SCHEMBL12527948 | 0.89 | ACE (0.39) | ACEMMEAPPFPR2 | |
| SCHEMBL17771420 | 0.89 | ACE (0.39) | ACEMMEAPPFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |