Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.55 |
| ▸ | MME | P08473 | 5/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12528549 | 0.93 | ACE (0.49) | ACEMMEAPP | |
| SCHEMBL30924361 | 0.89 | ACE (0.69) | ACEMMEAPP | |
| SCHEMBL30924359 | 0.89 | ACE (0.69) | ACEMMEAPP | |
| SCHEMBL17771396 | 0.88 | ACE (0.60) | ACEMMEAPP | |
| SCHEMBL12526771 | 0.88 | ACE (0.60) | ACEMMEAPP | |
| SCHEMBL12526743 | 0.86 | ACE (0.57) | ACEMMEAPP | |
| SCHEMBL12528551 | 0.83 | ACE (0.57) | ACEMMEAPP | |
| SCHEMBL12525793 | 0.83 | ACE (0.57) | ACEMMEAPP | |
| SCHEMBL17771412 | 0.83 | ACE (0.48) | ACEMMEAPP | |
| SCHEMBL12528474 | 0.83 | ACE (0.48) | ACEMMEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |