Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778283 | 0.87 | ADORA2A (0.43) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17769000 | 0.87 | ADORA2A (0.52) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17769018 | 0.85 | ADORA2A (0.50) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17778206 | 0.78 | ADORA2A (0.48) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17769157 | 0.77 | ADORA2A (0.46) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17768653 | 0.76 | ADORA2A (0.45) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17778078 | 0.76 | CNR1 (0.47) | ADORA2AADORA1 | |
| SCHEMBL17768910 | 0.76 | ADORA2A (0.46) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL20556554 | 0.75 | ADORA2A (0.47) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL17768608 | 0.75 | ADORA2A (0.53) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016081290-A1 | AMINOPYRAZINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME CORP. (US) | 2016-05-26 | — | — | WO | disclosed |