Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 6/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550448 | 1.00 | RAF1 (0.37) | RAF1FFAR4SCN10ALMNAMEN1 | |
| SCHEMBL20550447 | 1.00 | RAF1 (0.37) | RAF1FFAR4SCN10ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL20550370 | 0.99 | RAF1 (0.37) | RAF1FFAR4SCN10ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL17769614 | 0.99 | RAF1 (0.37) | RAF1FFAR4SCN10ALMNAMEN1 | |
| SCHEMBL20550498 | 0.96 | TRPV1 (0.38) | RAF1FFAR4SCN10ALMNAMEN1 | |
| SCHEMBL17769801 | 0.96 | TRPV1 (0.38) | RAF1FFAR4SCN10ALMNAMEN1 | |
| SCHEMBL20550854 | 0.96 | TRPV1 (0.38) | RAF1FFAR4SCN10ALMNAMEN1 | |
| SCHEMBL17769780 | 0.91 | RAF1 (0.38) | RAF1FFAR4KDM4ETRPV1BRAF | |
| SCHEMBL20550507 | 0.91 | RAF1 (0.38) | RAF1FFAR4KDM4ETRPV1BRAF | |
| SCHEMBL17769781 | 0.91 | RAF1 (0.38) | RAF1FFAR4KDM4ETRPV1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079712-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |