Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17768262 | 1.00 | GRM2 (0.38) | GRM2USP30MAPK1PDE10A | |
| SCHEMBL17778610 | 0.94 | GRM2 (0.37) | GRM2USP30MAPK1PDE10A | |
| SCHEMBL17768024 | 0.89 | USP30 (0.37) | GRM2USP30MAPK1PDE10A | |
| SCHEMBL19706604 | 0.89 | USP30 (0.37) | GRM2USP30MAPK1PDE10A | |
| SCHEMBL17767933 | 0.87 | USP30 (0.36) | GRM2USP30MAPK1PDE10A | |
| SCHEMBL17778721 | 0.86 | PDE10A (0.34) | MAPK1PDE10A | |
| SCHEMBL17768284 | 0.84 | RPS6KB1 (0.36) | — | |
| SCHEMBL17778513 | 0.84 | RPS6KB1 (0.36) | — | |
| SCHEMBL17778700 | 0.84 | MAPK1 (0.35) | GRM2USP30MAPK1PDE10A | |
| SCHEMBL17769292 | 0.83 | MAPK1 (0.37) | GRM2USP30MAPK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |