Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777481 | 0.99 | HRH3 (0.60) | HRH3KCNH2CYP3A4PDE4B | |
| SCHEMBL1776915 | 0.95 | HRH3 (0.61) | HRH3KCNH2CYP3A4PDE4B | |
| SCHEMBL1777134 | 0.94 | HRH3 (0.57) | HRH3KCNH2CYP3A4PDE4B | |
| SCHEMBL1178599 | 0.87 | HRH3 (0.59) | HRH3KCNH2 | |
| SCHEMBL1179574 | 0.84 | HRH3 (0.59) | HRH3KCNH2 | |
| SCHEMBL1179220 | 0.84 | HRH3 (0.59) | HRH3KCNH2 | |
| SCHEMBL3822481 | 0.83 | HRH3 (0.57) | HRH3KCNH2CYP3A4PDE4B | |
| SCHEMBL3850249 | 0.83 | HRH3 (0.57) | HRH3KCNH2CYP3A4PDE4B | |
| SCHEMBL3815871 | 0.83 | HRH3 (0.57) | HRH3KCNH2CYP3A4PDE4B | |
| SCHEMBL27738571 | 0.82 | HRH3 (0.59) | HRH3KCNH2CYP3A4PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-22 | — | — | US | claimed |
| US-7943605-B2 | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses | UCB PHARMA S.A. (BE) | 2011-05-17 | — | — | US | disclosed |
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | COASY, FURIN, PEPD | HRH3 3883/4885KCNH2 3895/4885CYP3A4 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.