Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1955102 | 0.91 | BCL2 (0.81) | BCL2 | |
| SCHEMBL19424700 | 0.87 | BCL2 (0.71) | BCL2 | |
| SCHEMBL1955105 | 0.86 | BCL2 (0.65) | BCL2 | |
| SCHEMBL1810749 | 0.80 | BCL2 (1.00) | BCL2 | |
| SCHEMBL30467960 | 0.80 | BCL2 (1.00) | BCL2 | |
| SCHEMBL2505947 | 0.80 | BCL2 (0.85) | BCL2 | |
| SCHEMBL19419663 | 0.79 | BCL2 (0.78) | BCL2 | |
| SCHEMBL1956220 | 0.79 | BCL2 (0.82) | BCL2 | |
| SCHEMBL1955004 | 0.79 | BCL2 (0.80) | BCL2 | |
| SCHEMBL1957132 | 0.78 | BCL2 (0.84) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376480-B1 | SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES | ABBVIE INC (US) | 2016-06-01 | — | — | EP | disclosed |