⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797067 | 0.77 | MCL1 (0.36) | — | |
| SCHEMBL1797065 | 0.77 | MCL1 (0.36) | — | |
| SCHEMBL4806613 | 0.72 | MCL1 (0.48) | — | |
| SCHEMBL2851442 | 0.72 | — | — | |
| SCHEMBL28506633 | 0.72 | — | — | |
| SCHEMBL2420340 | 0.72 | — | — | |
| SCHEMBL96571 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL5108516 | 0.70 | — | — | |
| SCHEMBL89220 | 0.67 | — | — | |
| SCHEMBL1777594 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556191-B2 | Aminoquinazoline derivatives and their salts and methods of use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-01-31 | — | — | US | disclosed |
| US-20160039838-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-11 | — | — | US | disclosed |
| WO-2014177038-A1 | AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-11-06 | — | — | WO | disclosed |
| US-7943612-B2 | Compounds that modulate PPAR activity, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090105481-A1 | Asymmetric Catalytic Hydrogenation of Prochiral Ketones and Aldehydes | SOLVIAS AG (CH) | 2009-04-23 | — | — | US | disclosed |
| US-20090048257-A1 | COMPOUNDS THAT MODULATE PPAR ACTIVITY, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS, LLC | 2009-02-19 | — | — | US | disclosed |
| EP-1993984-A1 | ASYMMETRIC CATALYTIC HYDROGENATION OF PROCHIRAL KETONES AND ALDEHYDES | Solvias AG (CH) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007104690-A1 | ASYMMETRIC CATALYTIC HYDROGENATION OF PROCHIRAL KETONES AND ALDEHYDES | SOLVIAS AG (CH) | 2007-09-20 | — | — | WO | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |