Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL925779 | 0.85 | MAPT (0.59) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL17786490 | 0.82 | MAPT (0.77) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL5130608 | 0.82 | MAPT (0.70) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL17786512 | 0.79 | KDM4E (0.67) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL27491848 | 0.79 | KDM4E (0.66) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL17786589 | 0.79 | MAPT (0.56) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL17786400 | 0.77 | CYP3A4 (0.47) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL926792 | 0.77 | HSD17B10 (0.48) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL27325970 | 0.77 | KDM4E (0.62) | MAPTKDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL17786640 | 0.76 | CYP1A2 (0.60) | MAPTKDM4EMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016083490-A1 | COMPOUNDS FOR THE TREATMENT OF AMYLOID-ASSOCIATED DISEASES | REMYND NV (BE) | 2016-06-02 | — | — | WO | disclosed |