Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787118 | 1.00 | CNR1 (0.49) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL17787117 | 1.00 | CNR1 (0.49) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL17793925 | 0.94 | CNR1 (0.51) | CNR1ALDH1A1CNR2FAAHTRPM8 | |
| SCHEMBL17793908 | 0.86 | CNR1 (0.51) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL19343062 | 0.84 | CNR1 (0.47) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL19328499 | 0.83 | CNR1 (0.46) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL17793982 | 0.83 | CNR1 (0.46) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL21644807 | 0.81 | CNR1 (0.44) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL19328506 | 0.81 | CNR1 (0.44) | CNR1ALDH1A1CNR2FAAHALOX12 | |
| SCHEMBL9905936 | 0.81 | CNR1 (0.63) | CNR1ALDH1A1CNR2FAAHALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016086136-A1 | FATTY ACID CYSTEAMINE CONJUGATES OF CFTR MODULATORS AND THEIR USE IN TREATING MEDICAL DISORDERS | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |
| WO-2016086136-A1 | FATTY ACID CYSTEAMINE CONJUGATES OF CFTR MODULATORS AND THEIR USE IN TREATING MEDICAL DISORDERS | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |