Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890146 | 1.00 | DHODH (0.39) | DHODHPARP1PTGES | |
| SCHEMBL1890148 | 1.00 | DHODH (0.39) | DHODHPARP1PTGES | |
| SCHEMBL12662490 | 0.91 | DHODH (0.40) | DHODHPARP1 | |
| SCHEMBL13551092 | 0.91 | DHODH (0.40) | DHODHPARP1 | |
| SCHEMBL12662505 | 0.89 | PRMT5 (0.38) | — | |
| SCHEMBL12662506 | 0.89 | PRMT5 (0.38) | — | |
| SCHEMBL13551097 | 0.87 | DHODH (0.39) | DHODH | |
| SCHEMBL13551098 | 0.87 | DHODH (0.39) | DHODH | |
| SCHEMBL13551088 | 0.87 | DHODH (0.39) | DHODH | |
| SCHEMBL13551087 | 0.87 | DHODH (0.39) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315763-B1 | BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2016-06-01 | — | — | EP | disclosed |