Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 9/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12662087 | 1.00 | P2RX1 (0.42) | P2RX1PARP1PYGLBRAFPTGES | |
| SCHEMBL17787698 | 0.93 | PARP1 (0.42) | PARP1BRAFPTGESKCNK3KCNK9 | |
| SCHEMBL12662463 | 0.93 | PARP1 (0.42) | PARP1BRAFPTGESKCNK3KCNK9 | |
| SCHEMBL12662102 | 0.93 | PARP1 (0.42) | PARP1PYGLPTGES | |
| SCHEMBL13551094 | 0.92 | P2RX1 (0.40) | P2RX1PARP1PYGLBRAFPTGES | |
| SCHEMBL12662540 | 0.92 | P2RX1 (0.40) | P2RX1PARP1PYGLBRAFPTGES | |
| SCHEMBL12662539 | 0.92 | P2RX1 (0.40) | P2RX1PARP1PYGLBRAFPTGES | |
| SCHEMBL1895828 | 0.91 | PARP1 (0.52) | PARP1PTGESKCNK3KCNK9RXFP1 | |
| SCHEMBL1895829 | 0.91 | PARP1 (0.52) | PARP1PTGESKCNK3KCNK9RXFP1 | |
| SCHEMBL12662488 | 0.89 | P2RX1 (0.38) | P2RX1PYGLPTGESMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315763-B1 | BENZIMIDAZOLES AND RELATED ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2016-06-01 | — | — | EP | disclosed |