Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785131 | 1.00 | SREBF2 (0.63) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL17785133 | 1.00 | SREBF2 (0.63) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL17791065 | 0.98 | SREBF2 (0.60) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL17790759 | 0.96 | SREBF2 (0.63) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL17790765 | 0.95 | SREBF2 (0.72) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL17790876 | 0.91 | SREBF2 (0.72) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL6520925 | 0.89 | SREBF2 (0.76) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL10331465 | 0.89 | SREBF2 (0.76) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL6526122 | 0.85 | SREBF2 (0.76) | SREBF2ALDH1A1CNR1RAB9ANPC1 | |
| SCHEMBL6526119 | 0.85 | SREBF2 (0.76) | SREBF2ALDH1A1CNR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016086103-A1 | FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |