SCHEMBL177932

SCHEMBL177932

CC(O)c1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4098469 1.00
SCHEMBL29419492 1.00
SCHEMBL2789978 1.00
SCHEMBL31080226 1.00
SCHEMBL30316657 1.00
Ammonia Solution, Strong SCHEMBL4915893 0.98 SMN1; SMN2 (0.59)
SCHEMBL2423599 0.83 SMN1; SMN2 (0.57)
SCHEMBL1242879 0.81 SMN1; SMN2 (0.87)
SCHEMBL10236 0.81
SCHEMBL6372762 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4466258-A1 NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2024-11-27 EP claimed
CN-118591534-A Novel benzimidazole pyridine derivatives 豪夫迈·罗氏有限公司 2024-09-03 CN claimed
WO-2023139085-A1 NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2023-07-27 WO claimed
CN-112876355-A Method for preparing carboxylic ester compound by breaking carbon-carbon bond through oxidation of secondary alcohol compound 中国科学院大连化学物理研究所 2021-06-01 CN claimed
CN-112724757-A Ionomer coating for eliminating surface charge, preparation method thereof and corresponding coating 徐宁 2021-04-30 CN claimed
CN-104263776-A Method for producing chiral pyridine ethanol through biological catalysis UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-01-07 CN claimed
EP-0304706-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS HAVING PYRIDINE SKELETONS CHISSO CORPORATION (JP) 1992-11-19 EP claimed
US-4996324-A Reacting secondary alcohol with primary alcohol in presence of basic catalyst BASF AKTIENGESELLSCHAFT (DE) 1991-02-26 US claimed
US-4971909-A TRANSESTERIFICATION IN THE PRESENCE OF HYDROLASES CHISSO CORPORATION (JP) 1990-11-20 US claimed
EP-0304706-A2 Process for producing optically active compounds having pyridine skeletons CHISSO CORPORATION (JP) 1989-03-01 EP claimed
CN-122011867-A Ionomer coatings for eliminating surface charge, method for preparing same and corresponding coatings 徐宁 2026-05-12 CN disclosed
EP-4735441-A1 PYRROLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF MENTAL ILLNESSES Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20260055113-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE INC. (US) 2026-02-26 US disclosed
US-12552796-B2 EED inhibitor, and preparation method therefor and use thereof JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) 2026-02-17 US disclosed
US-12545684-B2 CDK2 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2026-02-10 US disclosed
CN-88100804-A Substituted amine derivatives, their preparation and use 1988-08-24 CN disclosed
CN-87101830-A DICHLOROANILINE DERIVATIVES 1987-09-09 CN disclosed
EP-0234729-A2 Quinone derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-09-02 EP disclosed
EP-0227057-A2 Process for the preparation of substituted alcanols in 1-position by aromatic or heterocyclic groups BASF Aktiengesellschaft (DE) 1987-07-01 EP disclosed
US-4546198-A Asymmetric synthesis of esters and acids SHELL OIL COMPANY (US) 1985-10-08 US disclosed