Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793920 | 0.92 | EPHX2 (0.52) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17793959 | 0.92 | EPHX2 (0.48) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17793927 | 0.91 | EPHX2 (0.47) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17794026 | 0.89 | EPHX2 (0.45) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17793910 | 0.89 | EPHX2 (0.45) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17787216 | 0.89 | EPHX2 (0.53) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17793991 | 0.88 | EPHX2 (0.52) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17793926 | 0.88 | EPHX2 (0.51) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17793924 | 0.88 | EPHX2 (0.44) | EPHX2CNR1FAAHCNR2ALDH1A1 | |
| SCHEMBL17793970 | 0.88 | EPHX2 (0.44) | EPHX2CNR1FAAHCNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016086136-A1 | FATTY ACID CYSTEAMINE CONJUGATES OF CFTR MODULATORS AND THEIR USE IN TREATING MEDICAL DISORDERS | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |