Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 5/20 | 0.37 |
| ▸ | MYC | P01106 | 2/20 | 0.37 |
| ▸ | MAX | P61244 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775429 | 0.81 | EP300 (0.69) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL21137831 | 0.79 | EP300 (0.64) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL24089198 | 0.74 | EP300 (0.81) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL17784957 | 0.72 | EP300 (0.58) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL16392526 | 0.71 | MEN1 (0.58) | EP300 | |
| SCHEMBL16392473 | 0.70 | BCL2 (0.83) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL16392498 | 0.70 | EP300 (0.55) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL16392535 | 0.70 | EP300 (0.55) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL17784958 | 0.70 | EP300 (0.55) | EP300BCL2BCL2L1MCL1BAK1 | |
| SCHEMBL16392463 | 0.70 | EP300 (0.57) | EP300BCL2BCL2L1MCL1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016082934-A1 | NOVEL CYSTOBACTAMIDES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2016-06-02 | — | — | WO | disclosed |