Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 7/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17796027 | 0.91 | BCL2 (0.66) | BCL2BCL2L1 | |
| SCHEMBL1958659 | 0.86 | BCL2 (0.79) | BCL2 | |
| SCHEMBL1957183 | 0.85 | BCL2 (0.77) | BCL2BCL2L1 | |
| SCHEMBL1958953 | 0.83 | BCL2 (0.78) | BCL2 | |
| SCHEMBL1956318 | 0.80 | BCL2 (0.78) | BCL2BCL2L1 | |
| SCHEMBL1955194 | 0.80 | BCL2 (0.80) | BCL2BCL2L1 | |
| SCHEMBL1955503 | 0.80 | BCL2 (0.79) | BCL2BCL2L1 | |
| SCHEMBL1743443 | 0.79 | BCL2 (1.00) | BCL2BCL2L1 | |
| SCHEMBL1957182 | 0.79 | BCL2 (0.64) | BCL2BCL2L1 | |
| SCHEMBL1954930 | 0.79 | BCL2 (0.77) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3028702-A1 | METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS | AbbVie Bahamas Limited (BS) | 2016-06-08 | — | — | EP | disclosed |