Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 17/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1955205 | 0.95 | BCL2 (0.87) | BCL2 | |
| SCHEMBL1956887 | 0.92 | BCL2 (0.80) | BCL2 | |
| SCHEMBL1956054 | 0.89 | BCL2 (0.87) | BCL2 | |
| SCHEMBL1958076 | 0.88 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1957813 | 0.88 | BCL2 (0.81) | BCL2 | |
| SCHEMBL1958702 | 0.87 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1957017 | 0.87 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1956992 | 0.86 | — | — | |
| SCHEMBL1958175 | 0.86 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1958007 | 0.85 | BCL2 (1.00) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3028702-A1 | METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS | AbbVie Bahamas Limited (BS) | 2016-06-08 | — | — | EP | disclosed |