Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10556725 | 0.91 | TDP1 (0.58) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL10554618 | 0.91 | TDP1 (0.58) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL18211041 | 0.89 | TDP1 (0.56) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL18211042 | 0.89 | TDP1 (0.56) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL25473109 | 0.86 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL12246385 | 0.86 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL13744749 | 0.86 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL24167474 | 0.84 | TDP1 (0.44) | TDP1ALDH1A1RXRA | |
| SCHEMBL8777494 | 0.83 | TDP1 (0.68) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL12895952 | 0.83 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803047-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170158808-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | UNIV NEW YORK STATE RES FOUND (US) | 2017-06-08 | — | — | US | disclosed |
| US-9624338-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160159972-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158808-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | PARG, PARN, TRPC4 | TDP1 2937/4885L3MBTL1 2575/4885DNM1 96/4885 |
| US-20160159972-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | PARG, PARN, TRPC4 | TDP1 2937/4885L3MBTL1 2575/4885DNM1 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.