⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545929 | 0.83 | — | — | |
| SCHEMBL8943397 | 0.72 | — | — | |
| SCHEMBL9807603 | 0.72 | — | — | |
| SCHEMBL5818763 | 0.72 | — | — | |
| SCHEMBL5522044 | 0.65 | — | — | |
| SCHEMBL7784019 | 0.63 | MAP3K14 (0.46) | — | |
| SCHEMBL17845702 | 0.59 | — | — | |
| SCHEMBL15705535 | 0.59 | — | — | |
| SCHEMBL993368 | 0.57 | — | — | |
| SCHEMBL3573579 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9937224-B2 | Modulation of axon degeneration | GENENTECH, INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160161470-A1 | MODULATION OF AXON DEGENERATION | GENENTECH, INC. | 2016-06-09 | — | — | US | disclosed |